When the free-spirited, jazz-loving Prince Naveen of Maldonia comes to town, a deal with a shady voodoo doctor goes bad and the once suave royal is turned into a frog. In a desperate attempt to be human again, a favour in exchange for a fateful kiss on the lips from the beautiful girl, Tiana, takes an unexpected turn and leads them both on a hilarious adventure through the mystical bayous of Louisiana to the banks of the almighty Mississippi and back in time for Mardi Gras in New Orleans.