THE BIG SICK tells the story of Pakistan-born aspiring comedian Kumail (Nanjiani), who connects with grad student Emily (Zoe Kazan) after one of his standup sets. However, what they thought would be just a one-night stand blossoms into the real thing, which complicates the life that is expected of Kumail by his traditional Muslim parents. Then Emily is beset with a mystery illness forcing Kumail to navigate the medical crisis with her parents, Beth and Terry (Holly Hunter and Ray Romano) who he's never met, while dealing with the emotional tug-of-war between his family and his heart. Consumer Advice: (M) Coarse language and sexual references